ExpandOne-third of suzetrigine prescriptions (33.0%) were written in encounters with a diagnosis of chronic pain, compared with 6.7% of opioid prescriptions. Opioids were most often prescribed during encounters with evidence of surgery (48.8%) and acute pain (19.8%) compared to 10.2% and 31.8%, respectively, for suzetrigine.
ExpandOne-third of suzetrigine prescriptions (33.0%) were written in encounters with a diagnosis of chronic pain, compared with 6.7% of opioid prescriptions. Opioids were most often prescribed during encounters with evidence of surgery (48.8%) and acute pain (19.8%) compared to 10.2% and 31.8%, respectively, for suzetrigine.
ExpandAmong adults who have had a documented substance overdose, those who started on a GLP-1 had a 39% lower risk of a repeat overdose within three years of their overdose compared to patients who were never prescribed a GLP-1. Patients who started and later discontinued a GLP-1 still had a 20% lower risk than patients who never used a GLP-1.
ExpandAmong adults aged 40–79 with stage 1 hypertension, treatment eligibility rose modestly from 45.2% under the 2017 guideline to 47.0% under the 2025 guideline. Overall, 3.2% of patients would be treated differently under the new guideline (2.5% gained eligibility, 0.7% lost eligibility).
ExpandAmong adult patients living in states that have legalized sports betting, the quarterly rate of diagnosed gambling disorder rose from 3.0 per 100,000 patients in Q1 2018 to 4.8 per 100,000 in Q1 2026, around a 61% increase.
ExpandAmong adult patients living in states that have legalized sports betting, the quarterly rate of diagnosed gambling disorder rose from 3.0 per 100,000 patients in Q1 2018 to 4.8 per 100,000 in Q1 2026, around a 61% increase.
ExpandBased on colorectal cancer detection rates among more than 3 million screening-eligible adults, our model estimates that at age 40 approximately 111 cancers would be detected per 100,000 screenings, compared with 159 per 100,000 screenings at age 45, the current recommended starting age. Based on the model, this equates to nearly 44% more 40-year-olds needing to be screened to detect one colorectal cancer (CRC) case compared to the number of 45-year-olds who would need to be screened.
ExpandBased on colorectal cancer detection rates among more than 3 million screening-eligible adults, our model estimates that at age 40 approximately 111 cancers would be detected per 100,000 screenings, compared with 159 per 100,000 screenings at age 45, the current recommended starting age. Based on the model, this equates to nearly 44% more 40-year-olds needing to be screened to detect one colorectal cancer (CRC) case compared to the number of 45-year-olds who would need to be screened.
ExpandAt 15 months post-treatment, 12.5% of bariatric surgery patients had a new diagnosis of nutritional or iron-deficiency anemia, compared to 4.6% of GLP-1 patients and 3.8% of patients on other weight-loss medications.
ExpandAt 15 months post-treatment, 12.5% of bariatric surgery patients had a new diagnosis of nutritional or iron-deficiency anemia, compared to 4.6% of GLP-1 patients and 3.8% of patients on other weight-loss medications.
ExpandThe share of outpatient encounters with a systemic antibiotic prescription fell from 10.4% pre-pandemic to 8.0% during the pandemic and partially returned to pre-pandemic levels at 9.1% post-pandemic.
ExpandThe share of outpatient encounters with a systemic antibiotic prescription fell from 10.4% pre-pandemic to 8.0% during the pandemic and partially returned to pre-pandemic levels at 9.1% post-pandemic.
ExpandMale patients aged 10 to 15 who had an ED visit for a motor vehicle crash (MVC) were as much as four times as likely to experience a subsequent firearm injury compared with those whose ED visit was for a fall, in some parts of the United States.
ExpandThe risks of myocardial infarction (MI), ischemic stroke, and hemorrhagic stroke are increased for patients with high or low average systolic blood pressure (BP). The risks are greater at very low systolic BP than at very high systolic BP.
ExpandAt 24 months post-cessation, 56% of semaglutide, 52% of liraglutide, and 55% of tirzepatide patients kept the weight off or lost additional weight.
ExpandMale patients aged 10 to 15 who had an ED visit for a motor vehicle crash (MVC) were as much as four times as likely to experience a subsequent firearm injury compared with those whose ED visit was for a fall, in some parts of the United States.
ExpandThe risks of myocardial infarction (MI), ischemic stroke, and hemorrhagic stroke are increased for patients with high or low average systolic blood pressure (BP). The risks are greater at very low systolic BP than at very high systolic BP.
ExpandAt 24 months post-cessation, 56% of semaglutide, 52% of liraglutide, and 55% of tirzepatide patients kept the weight off or lost additional weight.
ExpandThree months after stopping a GLP-1, 40% of patients had further improved their HbA1c compared to when they discontinued the GLP-1, 48% kept some of their improvement, and just 12% had a worse HbA1c compared to their pre-GLP-1 level.
ExpandMale patients aged 10 to 15 who had an ED visit for a motor vehicle crash (MVC) were as much as four times as likely to experience a subsequent firearm injury compared with those whose ED visit was for a fall, in some parts of the United States.
ExpandThe risks of myocardial infarction (MI), ischemic stroke, and hemorrhagic stroke are increased for patients with high or low average systolic blood pressure (BP). The risks are greater at very low systolic BP than at very high systolic BP.
ExpandAt 24 months post-cessation, 56% of semaglutide, 52% of liraglutide, and 55% of tirzepatide patients kept the weight off or lost additional weight.
